{"id":7228,"date":"2026-05-15T12:53:18","date_gmt":"2026-05-15T12:53:18","guid":{"rendered":"https:\/\/apexnewssl.com\/?p=7228"},"modified":"2026-05-15T12:53:18","modified_gmt":"2026-05-15T12:53:18","slug":"colon-cancer","status":"publish","type":"post","link":"https:\/\/apexnewssl.com\/?p=7228","title":{"rendered":"Colon Cancer"},"content":{"rendered":"<p><strong>Colon Cancer:<\/strong> Malignant tumor of the colon, usually adenocarcinoma, commonly arising from adenomatous polyps through the adenoma-carcinoma sequence. Early detection by screening is very important.<\/p>\n<p><strong>Risk Factors<\/strong><\/p>\n<ul>\n<li>Increasing age<\/li>\n<li>Family history of colorectal cancer \/ Lynch syndrome \/ FAP<\/li>\n<li>Adenomatous polyps, inflammatory bowel disease<\/li>\n<li>Diet high in red\/processed meat, obesity, smoking, alcohol<\/li>\n<\/ul>\n<p><strong>Pathology<\/strong><\/p>\n<ul>\n<li>Usually adenocarcinoma<\/li>\n<li>Often develops from a colonic polyp over time<\/li>\n<\/ul>\n<p><strong>Clinical Features<\/strong><\/p>\n<ul>\n<li>Occult or overt blood in stool<\/li>\n<li>Change in bowel habits: constipation, diarrhea, narrow stools<\/li>\n<li>Iron deficiency anemia, fatigue, weight loss<\/li>\n<li>Abdominal pain or bowel obstruction in advanced disease<\/li>\n<\/ul>\n<p><strong>Right vs Left Colon Cancer<\/strong><\/p>\n<p><strong>Right-sided:<\/strong> occult bleeding, iron deficiency anemia, weakness<\/p>\n<p><strong>Left-sided:<\/strong> change in bowel habits, colicky pain, obstruction, visible blood in stool<\/p>\n<p><strong>Diagnosis<\/strong><\/p>\n<ul>\n<li>Colonoscopy with biopsy = diagnostic test of choice<\/li>\n<li>Staging done with imaging after histologic confirmation<\/li>\n<li>CEA may be used mainly for follow-up, not screening<\/li>\n<\/ul>\n<p><strong>Spread<\/strong><\/p>\n<ul>\n<li>Spreads first to regional lymph nodes<\/li>\n<li>Common distant metastasis site: liver<\/li>\n<li>Lung metastasis may also occur<\/li>\n<\/ul>\n<p><strong>Management<\/strong><\/p>\n<ul>\n<li>Surgical resection = main treatment for localized colon cancer<\/li>\n<li>Chemotherapy for node-positive or advanced disease<\/li>\n<li>Targeted therapy \/ immunotherapy may be used in selected advanced cases based on biomarkers<\/li>\n<\/ul>\n<p><strong>Prevention \/ Screening<\/strong><\/p>\n<ul>\n<li>Screening helps detect polyps and early cancer<\/li>\n<li>Average-risk adults are generally advised to begin colorectal cancer screening at age 45<\/li>\n<\/ul>\n<p><strong>High-Yield Points<\/strong><\/p>\n<ul>\n<li>Most colon cancers are adenocarcinomas<\/li>\n<li>Right colon = anemia<\/li>\n<li>Left colon = obstruction\/change in bowel habits<\/li>\n<li>Liver is the most common metastatic sit<\/li>\n<\/ul>\n<p><strong>\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Colon Cancer: Malignant tumor of the colon, usually adenocarcinoma, commonly arising from adenomatous polyps through&#8230;<\/p>\n","protected":false},"author":1,"featured_media":7229,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","om_disable_all_campaigns":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[14],"tags":[],"class_list":["post-7228","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Colon Cancer - Apexnewssl.com<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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